N‐terminally and C‐terminally truncated forms of glucose‐dependent insulinotropic polypeptide are high‐affinity competitive antagonists of the human GIP receptor

BACKGROUND AND PURPOSE: Glucose‐dependent insulinotropic polypeptide (GIP) affects lipid, bone and glucose homeostasis. High‐affinity ligands for the GIP receptor are needed to elucidate the physiological functions and pharmacological potential of GIP in vivo. GIP(1–30)NH(2) is a naturally occurring...

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Detalles Bibliográficos
Autores principales: Hansen, L S, Sparre‐Ulrich, A H, Christensen, M, Knop, F K, Hartmann, B, Holst, J J, Rosenkilde, M M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761099/
https://www.ncbi.nlm.nih.gov/pubmed/26572091
http://dx.doi.org/10.1111/bph.13384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761099/
https://www.ncbi.nlm.nih.gov/pubmed/26572091
http://dx.doi.org/10.1111/bph.13384

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