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Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory breast cancer cells in a signal transducer and activator of transcription 2 (STAT2)-dependent manner

BACKGROUND: Inflammatory breast cancer (IBC) is a very aggressive and lethal subtype of breast cancer that accounts for about 4 % of all breast cancers diagnosed in the United States. Despite the efforts of several investigators to identify the molecular factors driving the aggressive phenotype of I...

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Detalles Bibliográficos
Autores principales: Ogony, Joshua, Choi, Hye Joung, Lui, Asona, Cristofanilli, Massimo, Lewis-Wambi, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761146/
https://www.ncbi.nlm.nih.gov/pubmed/26897526
http://dx.doi.org/10.1186/s13058-016-0683-7