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The effects of sample size on population genomic analyses – implications for the tests of neutrality
BACKGROUND: One of the fundamental measures of molecular genetic variation is the Watterson’s estimator (θ), which is based on the number of segregating sites. The estimation of θ is unbiased only under neutrality and constant population growth. It is well known that the estimation of θ is biased wh...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761153/ https://www.ncbi.nlm.nih.gov/pubmed/26897757 http://dx.doi.org/10.1186/s12864-016-2441-8 |