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A novel anti-p21Ras scFv antibody reacting specifically with human tumour cell lines and primary tumour tissues
BACKGROUND: The ras genes play an important role in the development and progression of human tumours. Neutralizing Ras proteins in the cytoplasm could be an effective approach to blocking ras signalling. In this study, we prepared anti-p21Ras single chain fragment variable antibody (scFv) and invest...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761205/ https://www.ncbi.nlm.nih.gov/pubmed/26897358 http://dx.doi.org/10.1186/s12885-016-2168-6 |