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Tumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapy
OBJECTIVES: Paclitaxel (PTX) is frequently used in the clinical treatment of solid tumors. But the PTX-resistance is a great obstacle in cancer treatment. Exploration of the mechanisms of drug resistance suggests that tumor suppressor genes (TSGs) play a key role in the response of chemotherapeutic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761208/ https://www.ncbi.nlm.nih.gov/pubmed/26900348 http://dx.doi.org/10.1186/s12935-016-0290-9 |