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Constructing an integrated genetic and epigenetic cellular network for whole cellular mechanism using high-throughput next-generation sequencing data

BACKGROUND: Epigenetics has been investigated in cancer initiation, and development, especially, since the appearance of epigenomics. Epigenetics may be defined as the mechanisms that lead to heritable changes in gene function and without affecting the sequence of genome. These mechanisms explain ho...

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Detalles Bibliográficos
Autores principales: Chen, Bor-Sen, Li, Cheng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761210/
https://www.ncbi.nlm.nih.gov/pubmed/26897165
http://dx.doi.org/10.1186/s12918-016-0256-5