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A model qualification method for mechanistic physiological QSP models to support model‐informed drug development

Mechanistic physiological modeling is a scientific method that combines available data with scientific knowledge and engineering approaches to facilitate better understanding of biological systems, improve decision‐making, reduce risk, and increase efficiency in drug discovery and development. It is...

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Detalles Bibliográficos
Autor principal: Friedrich, CM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761232/
https://www.ncbi.nlm.nih.gov/pubmed/26933515
http://dx.doi.org/10.1002/psp4.12056