Dependence of Proximal GC Boxes and Binding Transcription Factors in the Regulation of Basal and Valproic Acid-Induced Expression of t-PA

Objective. Endothelial tissue-type plasminogen activator (t-PA) release is a pivotal response to protect the circulation from occluding thrombosis. We have shown that the t-PA gene is epigenetically regulated and greatly induced by the histone deacetylase (HDAC) inhibitor valproic acid (VPA). We now...

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Detalles Bibliográficos
Autores principales: Ulfhammer, Erik, Larsson, Pia, Magnusson, Mia, Karlsson, Lena, Bergh, Niklas, Jern, Sverker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761389/
https://www.ncbi.nlm.nih.gov/pubmed/26966581
http://dx.doi.org/10.1155/2016/7928681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761389/
https://www.ncbi.nlm.nih.gov/pubmed/26966581
http://dx.doi.org/10.1155/2016/7928681

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