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TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC trial): study protocol for a randomized controlled trial

BACKGROUND: Cervical intraepithelial neoplasia (CIN) is the premalignant condition of cervical cancer. Whereas not all high grade CIN lesions progress to cervical cancer, the natural history and risk of progression of individual lesions remain unpredictable. Therefore, high-grade CIN is currently tr...

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Detalles Bibliográficos
Autores principales: Koeneman, M. M., Kruse, A. J., Kooreman, L. F. S., zur Hausen, A., Hopman, A. H. N., Sep, S. J. S., Van Gorp, T., Slangen, B. F. M., van Beekhuizen, H. J., van de Sande, M., Gerestein, C. G., Nijman, H. W., Kruitwagen, R. F. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761416/
https://www.ncbi.nlm.nih.gov/pubmed/26897518
http://dx.doi.org/10.1186/s12885-016-2187-3