DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer

Dapper homolog (DACT) 2 is one of the Dact gene family members, which are important modulators of Wnt signaling pathway. We aim to clarify its epigenetic inactivation, biological function and clinical implication in colon cancer. DACT2 was silenced in five out of eight colon cancer cell lines, but r...

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Detalles Bibliográficos
Autores principales: Wang, S, Dong, Y, Zhang, Y, Wang, X, Xu, L, Yang, S, Li, X, Dong, H, Su, L, Ng, S S M, Chang, Z, Sung, J J, Zhang, X, Yu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761644/
https://www.ncbi.nlm.nih.gov/pubmed/25023701
http://dx.doi.org/10.1038/onc.2014.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761644/
https://www.ncbi.nlm.nih.gov/pubmed/25023701
http://dx.doi.org/10.1038/onc.2014.201

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