CUB-domain-containing protein 1 overexpression in solid cancers promotes cancer cell growth by activating Src family kinases

The transmembrane glycoprotein, CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein 1 (CDCP1) is overexpressed in several cancer types and is a predictor of poor prognosis for patients on standard of care therapies. Phosphorylation of CDCP1 tyrosine sites is induced upon loss of cell adhe...

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Detalles Bibliográficos
Autores principales: Leroy, C, Shen, Q, Strande, V, Meyer, R, McLaughlin, M E, Lezan, E, Bentires-Alj, M, Voshol, H, Bonenfant, D, Alex Gaither, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761645/
https://www.ncbi.nlm.nih.gov/pubmed/25728678
http://dx.doi.org/10.1038/onc.2015.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761645/
https://www.ncbi.nlm.nih.gov/pubmed/25728678
http://dx.doi.org/10.1038/onc.2015.19

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