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p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

Tumour cells often acquire the ability to escape cell death, a key event leading to the development of cancer. In almost half of all human cancers, the capability to induce cell death is reduced by the mutation and inactivation of p53, a tumour suppressor protein that is a central regulator of apopt...

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Detalles Bibliográficos
Autores principales: Long, J S, Schoonen, P M, Graczyk, D, O'Prey, J, Ryan, K M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761646/
https://www.ncbi.nlm.nih.gov/pubmed/25659586
http://dx.doi.org/10.1038/onc.2014.436