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p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death
Tumour cells often acquire the ability to escape cell death, a key event leading to the development of cancer. In almost half of all human cancers, the capability to induce cell death is reduced by the mutation and inactivation of p53, a tumour suppressor protein that is a central regulator of apopt...
Autores principales: | Long, J S, Schoonen, P M, Graczyk, D, O'Prey, J, Ryan, K M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761646/ https://www.ncbi.nlm.nih.gov/pubmed/25659586 http://dx.doi.org/10.1038/onc.2014.436 |
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