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Family-Based Multi-SNP X Chromosome Analysis Using Parent Information

We propose a method for association analysis of haplotypes on the X chromosome that offers both improved power and robustness to population stratification in studies of affected offspring and their parents if all three have been genotyped. The method makes use of assumed parental haplotype exchangea...

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Detalles Bibliográficos
Autores principales: Wise, Alison S., Shi, Min, Weinberg, Clarice R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761843/
https://www.ncbi.nlm.nih.gov/pubmed/26941777
http://dx.doi.org/10.3389/fgene.2016.00020