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Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons

Although the essential role of protein kinase B (PKB)/Akt in cell survival signaling has been clearly established, the mechanism by which Akt mediates the cellular response to hydrogen peroxide (H(2)O(2))-induced oxidative stress remains unclear. We demonstrated that Akt attenuated neuronal apoptosi...

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Detalles Bibliográficos
Autores principales: Park, Ji Hye, Kim, Chung Kwon, Lee, Sang Bae, Lee, Kyung-Hoon, Cho, Sung-Woo, Ahn, Jee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761890/
https://www.ncbi.nlm.nih.gov/pubmed/26899247
http://dx.doi.org/10.1038/srep21857