Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery

Pyrazolo[3,4-d]pyrimidines are a class of compounds with a good activity against several cancer cell lines. Despite the promising anticancer activity, these molecules showed a poor aqueous solubility. This issue could threat the future development of pyrazolo[3,4-d]pyrimidines as clinical drug candi...

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Detalles Bibliográficos
Autores principales: Vignaroli, Giulia, Calandro, Pierpaolo, Zamperini, Claudio, Coniglio, Federica, Iovenitti, Giulia, Tavanti, Matteo, Colecchia, David, Dreassi, Elena, Valoti, Massimo, Schenone, Silvia, Chiariello, Mario, Botta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761914/
https://www.ncbi.nlm.nih.gov/pubmed/26898318
http://dx.doi.org/10.1038/srep21509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761914/
https://www.ncbi.nlm.nih.gov/pubmed/26898318
http://dx.doi.org/10.1038/srep21509

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