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Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells

TIM4 (T cell immunoglobulin mucin domain molecule-4) plays a critical role in the initiation of skewed T helper (Th) 2 polarization. The factors regulating TIM4 expression are unclear. This study tests a hypothesis that p300 and STAT6 (signal transducer and activator transcription-6) regulates TIM4...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Li, Lin-Jing, Xu, Ling-Zhi, Liu, Jiang-Qi, Zhang, Huan-Ping, Geng, Xiao-Rui, Liu, Zhi-Gang, Yang, Ping-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761958/
https://www.ncbi.nlm.nih.gov/pubmed/26899911
http://dx.doi.org/10.1038/srep21336