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Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels

Gating charges in voltage-sensing domains (VSD) of voltage-sensitive ion channels and enzymes are carried on arginine side chains rather than lysine. This arginine preference may result from the unique hydration properties of the side chain guanidinium group which facilitates its movement through a...

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Detalles Bibliográficos
Autores principales: Armstrong, Craig T., Mason, Philip E., Anderson, J. L. Ross, Dempsey, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761985/
https://www.ncbi.nlm.nih.gov/pubmed/26899474
http://dx.doi.org/10.1038/srep21759