Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics

We present a new, rapid method for producing blood platelets in vitro from cultured megakaryocytes based on a microfluidic device. This device consists in a wide array of VWF-coated micropillars. Such pillars act as anchors on megakaryocytes, allowing them to remain trapped in the device and subject...

Descripción completa

Detalles Bibliográficos
Autores principales: Blin, Antoine, Le Goff, Anne, Magniez, Aurélie, Poirault-Chassac, Sonia, Teste, Bruno, Sicot, Géraldine, Nguyen, Kim Anh, Hamdi, Feriel S., Reyssat, Mathilde, Baruch, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761988/
https://www.ncbi.nlm.nih.gov/pubmed/26898346
http://dx.doi.org/10.1038/srep21700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761988/
https://www.ncbi.nlm.nih.gov/pubmed/26898346
http://dx.doi.org/10.1038/srep21700

Ejemplares similares