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EGCG in Green Tea Induces Aggregation of HMGB1 Protein through Large Conformational Changes with Polarized Charge Redistribution

As a major effective component in green tea, (−)-epigallocatechin-3-gallate (EGCG)’s potential benefits to human health have been widely investigated. Recent experimental evidences indicate that EGCG can induce the aggregation of HMGB1 protein, a late mediator of inflammation, which subsequently sti...

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Detalles Bibliográficos
Autores principales: Meng, Xuan-Yu, Li, Baoyu, Liu, Shengtang, Kang, Hongsuk, Zhao, Lin, Zhou, Ruhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762017/
https://www.ncbi.nlm.nih.gov/pubmed/26899177
http://dx.doi.org/10.1038/srep22128