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Analysis of chromatin fibers in Hela cells with electron tomography

The presence and folding pattern of chromatin in eukaryotic cells remain elusive and controversial. In this study, we prepared ultra-thin sections of Hela cells with three different fixation and sectioning methods, i.e., chemical fixation, high pressure freezing with freeze substitution, and cryo-ul...

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Detalles Bibliográficos
Autores principales: Li, Xiaomin, Feng, Hongli, Zhang, Jianguo, Sun, Lei, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762132/
https://www.ncbi.nlm.nih.gov/pubmed/26942219
http://dx.doi.org/10.1007/s41048-015-0009-9