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A new dimethyl labeling-based SID-MRM-MS method and its application to three proteases involved in insulin maturation

The absolute quantification of target proteins in proteomics involves stable isotope dilution coupled with multiple reactions monitoring mass spectrometry (SID-MRM-MS). The successful preparation of stable isotope-labeled internal standard peptides is an important prerequisite for the SID-MRM absolu...

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Detalles Bibliográficos
Autores principales: Cheng, Dongwan, Zheng, Li, Hou, Junjie, Wang, Jifeng, Xue, Peng, Yang, Fuquan, Xu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762191/
https://www.ncbi.nlm.nih.gov/pubmed/26942221
http://dx.doi.org/10.1007/s41048-015-0012-1