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A new dimethyl labeling-based SID-MRM-MS method and its application to three proteases involved in insulin maturation
The absolute quantification of target proteins in proteomics involves stable isotope dilution coupled with multiple reactions monitoring mass spectrometry (SID-MRM-MS). The successful preparation of stable isotope-labeled internal standard peptides is an important prerequisite for the SID-MRM absolu...
Autores principales: | Cheng, Dongwan, Zheng, Li, Hou, Junjie, Wang, Jifeng, Xue, Peng, Yang, Fuquan, Xu, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762191/ https://www.ncbi.nlm.nih.gov/pubmed/26942221 http://dx.doi.org/10.1007/s41048-015-0012-1 |
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