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Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts
Bottom-up proteomics relies on the use of proteases and is the method of choice for identifying thousands of protein groups in complex samples. Top-down proteomics has been shown to be robust for direct analysis of small proteins and offers a solution to the “peptide-to-protein” inference problem in...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762530/ https://www.ncbi.nlm.nih.gov/pubmed/26503891 http://dx.doi.org/10.1074/mcp.M114.047480 |