5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors

Early metastasis is still the most recalcitrant factor in the treatment of lung cancer patients. By analyzing the structures and comparing the docking scores of the known pharmacophores, the authors of this paper designed 5-(bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA)...

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Detalles Bibliográficos
Autores principales: Gan, Taiping, Wang, Yuji, Zhao, Ming, Wu, Jianhui, Yang, Jian, Peng, Shiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762582/
https://www.ncbi.nlm.nih.gov/pubmed/26937173
http://dx.doi.org/10.2147/DDDT.S93570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762582/
https://www.ncbi.nlm.nih.gov/pubmed/26937173
http://dx.doi.org/10.2147/DDDT.S93570

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