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A fully synthetic self-adjuvanting globo H-Based vaccine elicited strong T cell-mediated antitumor immunity

Therapeutic cancer vaccines based on the abnormal glycans expressed on cancer cells, such as the globo H antigen, have witnessed great progress in recent years. For example, the keyhole limpet hemocyanin (KLH) conjugate of globo H has been on clinical trials as a cancer vaccine. However, such vaccin...

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Detalles Bibliográficos
Autores principales: Zhou, Zhifang, Liao, Guochao, Mandal, Satadru S., Suryawanshi, Sharad, Guo, Zhongwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762603/
https://www.ncbi.nlm.nih.gov/pubmed/26918109
http://dx.doi.org/10.1039/c5sc01402f