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Transcriptional Auto-Regulation of RUNX1 P1 Promoter

RUNX1 a member of the family of runt related transcription factors (RUNX), is essential for hematopoiesis. The expression of RUNX1 gene is controlled by two promoters; the distal P1 promoter and the proximal P2 promoter. Several isoforms of RUNX1 mRNA are generated through the use of both promoters...

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Detalles Bibliográficos
Autores principales: Martinez, Milka, Hinojosa, Marcela, Trombly, Daniel, Morin, Violeta, Stein, Janet, Stein, Gary, Javed, Amjad, Gutierrez, Soraya E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762634/
https://www.ncbi.nlm.nih.gov/pubmed/26901859
http://dx.doi.org/10.1371/journal.pone.0149119