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Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

Drug resistance and tolerance greatly diminish the therapeutic potential of antibiotics against pathogens. Antibiotic tolerance by bacterial biofilms often leads to persistent infections, but its mechanisms are unclear. Here we use a proteomics approach, pulsed stable isotope labelling with amino ac...

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Detalles Bibliográficos
Autores principales: Chua, Song Lin, Yam, Joey Kuok Hoong, Hao, Piliang, Adav, Sunil S., Salido, May Margarette, Liu, Yang, Givskov, Michael, Sze, Siu Kwan, Tolker-Nielsen, Tim, Yang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762895/
https://www.ncbi.nlm.nih.gov/pubmed/26892159
http://dx.doi.org/10.1038/ncomms10750