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Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2
In this study we identified mechanisms at the colonic mucosa by which MUC2 mucin regulated the production of β-defensin in a proinflammatory milieu but functionally protected susceptible bacteria from its antimicrobial effects. The regulator role of MUC2 on production of β-defensin 2 in combination...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762903/ https://www.ncbi.nlm.nih.gov/pubmed/25921338 http://dx.doi.org/10.1038/mi.2015.27 |