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Nuclear matrix protein SMAR1 control regulatory T-cell fate during inflammatory bowel disease (IBD)

Regulatory T (T(reg)) cells are essential for self-tolerance and immune homeostasis. Transcription factor Foxp3, a positive regulator of T(reg) cell differentiation, has been studied to some extent. Signal transducer and activator of transcription factor 3 (STAT3) is known to negatively regulate Fox...

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Detalles Bibliográficos
Autores principales: Mirlekar, B, Ghorai, S, Khetmalas, M, Bopanna, R, Chattopadhyay, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762908/
https://www.ncbi.nlm.nih.gov/pubmed/25993445
http://dx.doi.org/10.1038/mi.2015.42