PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines

Changes in macrophage phenotype have been implicated in apoptotic cell-mediated immune modulation via induction of peroxisome proliferator-activated receptor-γ (PPARγ). In this study, we characterized PPARγ induction by apoptotic cell instillation over the course of bleomycin-induced lung injury in...

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Detalles Bibliográficos
Autores principales: Yoon, Y-S, Kim, S-Y, Kim, M-J, Lim, J-H, Cho, M-S, Kang, J L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762910/
https://www.ncbi.nlm.nih.gov/pubmed/25586556
http://dx.doi.org/10.1038/mi.2014.130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762910/
https://www.ncbi.nlm.nih.gov/pubmed/25586556
http://dx.doi.org/10.1038/mi.2014.130

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