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PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines
Changes in macrophage phenotype have been implicated in apoptotic cell-mediated immune modulation via induction of peroxisome proliferator-activated receptor-γ (PPARγ). In this study, we characterized PPARγ induction by apoptotic cell instillation over the course of bleomycin-induced lung injury in...
Autores principales: | Yoon, Y-S, Kim, S-Y, Kim, M-J, Lim, J-H, Cho, M-S, Kang, J L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762910/ https://www.ncbi.nlm.nih.gov/pubmed/25586556 http://dx.doi.org/10.1038/mi.2014.130 |
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