TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity

Myotonic dystrophy type 1 (DM1), the most common form of muscular dystrophy in adults, is caused by toxic RNAs produced from the mutant DM protein kinase (DMPK) gene. DM1 is characterized by progressive muscle wasting and weakness. Therapeutic strategies have mainly focused on targeting the toxic RN...

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Detalles Bibliográficos
Autores principales: Yadava, Ramesh S., Foff, Erin P., Yu, Qing, Gladman, Jordan T., Zheng, Timothy S., Mahadevan, Mani S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762946/
https://www.ncbi.nlm.nih.gov/pubmed/26901467
http://dx.doi.org/10.1371/journal.pone.0150192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762946/
https://www.ncbi.nlm.nih.gov/pubmed/26901467
http://dx.doi.org/10.1371/journal.pone.0150192

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