Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells

The activation induced cytosine deaminase (AID) mediates diversification of B cell immunoglobulin genes by the three distinct yet related processes of somatic hypermutation (SHM), class switch recombination (CSR), and gene conversion (GCV). SHM occurs in germinal center B cells, and the transcriptio...

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Detalles Bibliográficos
Autores principales: Williams, Alan M., Maman, Yaakov, Alinikula, Jukka, Schatz, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762950/
https://www.ncbi.nlm.nih.gov/pubmed/26900682
http://dx.doi.org/10.1371/journal.pone.0149146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762950/
https://www.ncbi.nlm.nih.gov/pubmed/26900682
http://dx.doi.org/10.1371/journal.pone.0149146

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