Cargando…

Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by overexpression of the transcription factors OCT4, SOX2, KLF4, and c-Myc holds great promise for the development of personalized cell replacement therapies. In an attempt to minimize the risk of chromosomal disruption and t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hermann, Andreas, Kim, Jeong Beom, Srimasorn, Sumitra, Zaehres, Holm, Reinhardt, Peter, Schöler, Hans R., Storch, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763001/ https://www.ncbi.nlm.nih.gov/pubmed/26977154 http://dx.doi.org/10.1155/2016/4736159

Ejemplares similares

Increased Neuronal Differentiation Efficiency in High Cell Density-Derived Induced Pluripotent Stem Cells
por: Srimasorn, Sumitra, et al.
Publicado: (2019)

Reprogramming to Pluripotency through a Somatic Stem Cell Intermediate
por: Marthaler, Adele G., et al.
Publicado: (2013)

Zfp296 Is a Novel, Pluripotent-Specific Reprogramming Factor
por: Fischedick, Gerrit, et al.
Publicado: (2012)

p53 connects tumorigenesis and reprogramming to pluripotency
por: Tapia, Natalia, et al.
Publicado: (2010)

bHLH Transcription Factor Math6 Antagonizes TGF-β Signalling in Reprogramming, Pluripotency and Early Cell Fate Decisions
por: Divvela, Satya Srirama Karthik, et al.
Publicado: (2019)

Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions
por: Joo, Jin Young, et al.
Publicado: (2014)

Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene
por: Lee, Hyunah, et al.
Publicado: (2016)

ERRATUM: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions
por: Joo, Jin Young, et al.
Publicado: (2015)

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
por: Lee, Hyunah, et al.
Publicado: (2020)

Biological importance of OCT transcription factors in reprogramming and development
por: Kim, Kee-Pyo, et al.
Publicado: (2021)

Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
por: Malik, Vikas, et al.
Publicado: (2019)

Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency
por: Tiemann, Ulf, et al.
Publicado: (2014)

Epigenetic Aberrations Are Not Specific to Transcription Factor-Mediated Reprogramming
por: Tiemann, Ulf, et al.
Publicado: (2015)

Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming
por: Ruiz, Sergio, et al.
Publicado: (2013)

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein
por: Ehrlich, Marc, et al.
Publicado: (2015)

Self-Reprogramming of Spermatogonial Stem Cells into Pluripotent Stem Cells without Microenvironment of Feeder Cells
por: Lee, Seung-Won, et al.
Publicado: (2018)

Induced pluripotent stem cells free of exogenous reprogramming factors
por: Abujarour, Ramzey, et al.
Publicado: (2009)

Virus free induction of pluripotency and subsequent excision of reprogramming factors
por: Kaji, Keisuke, et al.
Publicado: (2009)

Two Factor Reprogramming of Human Neural Stem Cells into Pluripotency
por: Hester, Mark E., et al.
Publicado: (2009)

Identification of New Transcription Factors that Can Promote Pluripotent Reprogramming
por: Huang, Ping, et al.
Publicado: (2021)

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
por: Chuang, Wenpo, et al.
Publicado: (2017)

SIRT2 is required for efficient reprogramming of mouse embryonic fibroblasts toward pluripotency
por: Kim, Ah-Young, et al.
Publicado: (2018)

Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis
por: Nam, Donggyu, et al.
Publicado: (2022)

Trib2 regulates the pluripotency of embryonic stem cells and enhances reprogramming efficiency
por: Do, Eun Kyoung, et al.
Publicado: (2017)

R-loops coordinate with SOX2 in regulating reprogramming to pluripotency
por: Li, Yaoyi, et al.
Publicado: (2020)

Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells
por: Wu, Guangming, et al.
Publicado: (2011)

In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
por: Yilmazer, Açelya, et al.
Publicado: (2013)

Reprogramming to Pluripotency Using Designer TALE Transcription Factors Targeting Enhancers
por: Gao, Xuefei, et al.
Publicado: (2013)

Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons
por: Oh, Seung-ick, et al.
Publicado: (2014)

Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions
por: Frank, Stefan, et al.
Publicado: (2012)

Reprogramming barriers and enhancers: strategies to enhance the efficiency and kinetics of induced pluripotency
por: Ebrahimi, Behnam
Publicado: (2015)

Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency
por: Xu, Peng, et al.
Publicado: (2019)

Reprogramming efficiency and pluripotency of mule iPSCs over its parents
por: Zhang, Jia, et al.
Publicado: (2023)

Direct neuronal reprogramming by temporal identity factors
por: Boudreau-Pinsonneault, Camille, et al.
Publicado: (2023)

Aberrant DNA methylation reprogramming during induced pluripotent stem cell generation is dependent on the choice of reprogramming factors
por: Planello, Aline C, et al.
Publicado: (2014)

Nanog-Independent Reprogramming to iPSCs with Canonical Factors
por: Carter, Ava C., et al.
Publicado: (2014)

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors
por: Yilmazer, Açelya, et al.
Publicado: (2013)

Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency
por: Fu, Meijun, et al.
Publicado: (2021)

Molecular mechanisms of pluripotency and reprogramming
por: Na, Jie, et al.
Publicado: (2010)

Linking Pluripotency Reprogramming and Cancer
por: Iglesias, Juan Manuel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_cdsgmc966k6kh0p97jd531klnd