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IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain

The generation of neurons in the adult mammalian brain requires the activation of quiescent neural stem cells (NSCs). This activation and the sequential steps of neuron formation from NSCs are regulated by a number of stimuli, which include growth factors. Insulin-like growth factor-I (IGF-I) exert...

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Detalles Bibliográficos
Autores principales: Nieto-Estévez, Vanesa, Defterali, Çağla, Vicario-Abejón, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763060/
https://www.ncbi.nlm.nih.gov/pubmed/26941597
http://dx.doi.org/10.3389/fnins.2016.00052