The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus

Previous studies showed that type 2 diabetes mellitus (T2DM) is linked to increased risk of developing colon cancer. Insulin and insulin-like growth factor 1 (IGF-1) are increased in patients with T2DM. The increased insulin and IGF-1 may be responsible for the developing of colon cancer. In this st...

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Detalles Bibliográficos
Autores principales: Teng, Jia-An, Wu, San-Gang, Chen, Jia-Xin, Li, Qiang, Peng, Fang, Zhu, Zhou, Qin, Jian, He, Zhen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763097/
https://www.ncbi.nlm.nih.gov/pubmed/26901856
http://dx.doi.org/10.1371/journal.pone.0149822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763097/
https://www.ncbi.nlm.nih.gov/pubmed/26901856
http://dx.doi.org/10.1371/journal.pone.0149822

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