Cargando…

A functional AT/G polymorphism in the 5′-untranslated region of SETDB2 in the IgE locus on human chromosome 13q14

The immunoglobulin E (IgE)-associated locus on human chromosome 13q14 influencing asthma-related traits contains the genes PHF11 and SETDB2. SETDB2 is located in the same linkage disequilibrium region as PHF11 and polymorphisms within SETDB2 have been shown to associate with total serum IgE levels....

Descripción completa

Detalles Bibliográficos
Autores principales: Holt, R J, Vandiedonck, C, Willis-Owen, S A, Knight, J C, Cookson, W O, Moffatt, M F, Zhang, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763160/
https://www.ncbi.nlm.nih.gov/pubmed/26378653
http://dx.doi.org/10.1038/gene.2015.36