A potential therapeutic peptide-based neutralizer that potently inhibits Shiga toxin 2 in vitro and in vivo

Shiga toxin 2 (Stx2) is a major virulence factor in infections with Stx-producing Escherichia coli (STEC), which can cause serious clinical complications in humans, such as hemolytic uremic syndrome (HUS). Recently, we screened and identified two peptide-based Stx2 neutralizers, TF-1 and WA-8, which...

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Detalles Bibliográficos
Autores principales: Li, Tao, Tu, Wei, Liu, Yuenan, Zhou, Peng, Cai, Kun, Li, Zhan, Liu, Xiong, Ning, Nianzhi, Huang, Jie, Wang, Shenghan, Huang, Jian, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763182/
https://www.ncbi.nlm.nih.gov/pubmed/26903273
http://dx.doi.org/10.1038/srep21837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763182/
https://www.ncbi.nlm.nih.gov/pubmed/26903273
http://dx.doi.org/10.1038/srep21837

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