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Isolation of a recombinant antibody specific for a surface marker of the corneal endothelium by phage display

Cell surface antigens are important targets for monoclonal antibodies, but they are often difficult to work with due to their association with the cell membrane. Phage display is a versatile technique that can be applied to generate binders against difficult targets. Here we used antibody phage disp...

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Detalles Bibliográficos
Autores principales: Dorfmueller, Simone, Tan, Hwee Ching, Ngoh, Zi Xian, Toh, Kai Yee, Peh, Gary, Ang, Heng-Pei, Seah, Xin-Yi, Chin, Angela, Choo, Andre, Mehta, Jodhbir S., Sun, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763205/
https://www.ncbi.nlm.nih.gov/pubmed/26902886
http://dx.doi.org/10.1038/srep21661