Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model

Liver dysfunction is an early event in sepsis-related multi-organ failure. We here report the establishment and characterization of a microfluidically supported in vitro organoid model of the human liver sinusoid. The liver organoid is composed of vascular and hepatocyte cell layers integrating non-...

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Detalles Bibliográficos
Autores principales: Gröger, Marko, Rennert, Knut, Giszas, Benjamin, Weiß, Elisabeth, Dinger, Julia, Funke, Harald, Kiehntopf, Michael, Peters, Frank T., Lupp, Amelie, Bauer, Michael, Claus, Ralf A., Huber, Otmar, Mosig, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763209/
https://www.ncbi.nlm.nih.gov/pubmed/26902749
http://dx.doi.org/10.1038/srep21868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763209/
https://www.ncbi.nlm.nih.gov/pubmed/26902749
http://dx.doi.org/10.1038/srep21868

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