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Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model
Liver dysfunction is an early event in sepsis-related multi-organ failure. We here report the establishment and characterization of a microfluidically supported in vitro organoid model of the human liver sinusoid. The liver organoid is composed of vascular and hepatocyte cell layers integrating non-...
Autores principales: | Gröger, Marko, Rennert, Knut, Giszas, Benjamin, Weiß, Elisabeth, Dinger, Julia, Funke, Harald, Kiehntopf, Michael, Peters, Frank T., Lupp, Amelie, Bauer, Michael, Claus, Ralf A., Huber, Otmar, Mosig, Alexander S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763209/ https://www.ncbi.nlm.nih.gov/pubmed/26902749 http://dx.doi.org/10.1038/srep21868 |
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