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A common mechanism involving the TORC1 pathway can lead to amphotericin B-persistence in biofilm and planktonic Saccharomyces cerevisiae populations

Fungal infections are an increasing clinical problem. Decreased treatment effectiveness is associated with biofilm formation and drug recalcitrance is thought to be biofilm specific. However, no systematic investigations have tested whether resistance mechanisms are shared between biofilm and plankt...

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Detalles Bibliográficos
Autores principales: Bojsen, Rasmus, Regenberg, Birgitte, Gresham, David, Folkesson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763212/
https://www.ncbi.nlm.nih.gov/pubmed/26903175
http://dx.doi.org/10.1038/srep21874