How can macromolecular crowding inhibit biological reactions? The enhanced formation of DNA nanoparticles

In contrast to the already known effect that macromolecular crowding usually promotes biological reactions, solutions of PEG 6k at high concentrations stop the cleavage of DNA by HindIII enzyme, due to the formation of DNA nanoparticles. We characterized the DNA nanoparticles and probed the prerequi...

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Detalles Bibliográficos
Autores principales: Hou, Sen, Trochimczyk, Piotr, Sun, Lili, Wisniewska, Agnieszka, Kalwarczyk, Tomasz, Zhang, Xuzhu, Wielgus-Kutrowska, Beata, Bzowska, Agnieszka, Holyst, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763241/
https://www.ncbi.nlm.nih.gov/pubmed/26903405
http://dx.doi.org/10.1038/srep22033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763241/
https://www.ncbi.nlm.nih.gov/pubmed/26903405
http://dx.doi.org/10.1038/srep22033

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