Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment

Pygo2 has been discovered as an important Wnt signaling component contributing to the activation of Wnt-target gene transcription. In the present study, we discovered that Pygo2 mRNA and protein levels were up-regulated in the majority of (152/209) human brain glioma tissues and five glioma cell lin...

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Detalles Bibliográficos
Autores principales: Zhou, Cefan, Zhang, Yi, Dai, Jun, Zhou, Mengzhou, Liu, Miao, Wang, Yefu, Chen, Xing-Zhen, Tang, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763266/
https://www.ncbi.nlm.nih.gov/pubmed/26902498
http://dx.doi.org/10.1038/srep22066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763266/
https://www.ncbi.nlm.nih.gov/pubmed/26902498
http://dx.doi.org/10.1038/srep22066

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