Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis

BACKGROUND: Tumor necrosis factor (TNF) has pleiotropic functions during both the demyelinating autoimmune disease multiple sclerosis (MS) and its murine model experimental autoimmune encephalomyelitis (EAE). How TNF regulates disability during progressive disease remains unresolved. Using a progres...

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Detalles Bibliográficos
Autores principales: Valentin-Torres, Alice, Savarin, Carine, Hinton, David R., Phares, Timothy W., Bergmann, Cornelia C., Stohlman, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763407/
https://www.ncbi.nlm.nih.gov/pubmed/26906225
http://dx.doi.org/10.1186/s12974-016-0513-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763407/
https://www.ncbi.nlm.nih.gov/pubmed/26906225
http://dx.doi.org/10.1186/s12974-016-0513-y

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