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Oxyboration with and without a Catalyst: Borylated Isoxazoles via B–O σ-Bond Addition

[Image: see text] Herein we report an oxyboration reaction with activated substrates that employs B–O σ bond additions to C–C π bonds to form borylated isoxazoles, which are potential building blocks for drug discovery. Although this reaction can be effectively catalyzed by gold, it is the first exa...

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Detalles Bibliográficos
Autores principales: Tu, Kim N., Hirner, Joshua J., Blum, Suzanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763986/
https://www.ncbi.nlm.nih.gov/pubmed/26771389
http://dx.doi.org/10.1021/acs.orglett.5b03530