Calcium-induced tetramerization and zinc chelation shield human calprotectin from degradation by host and bacterial extracellular proteases

Calprotectin (CP, S100A8/S100A9 oligomer, MRP-8/14 oligomer, calgranulins A and B) is a protein component of the innate immune system that contributes to the metal-withholding response by sequestering bioavailable transition metal ions at sites of infection. Human CP employs Ca(ii) ions to modulate...

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Detalles Bibliográficos
Autores principales: Stephan, Jules R., Nolan, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763987/
https://www.ncbi.nlm.nih.gov/pubmed/26925211
http://dx.doi.org/10.1039/c5sc03287c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763987/
https://www.ncbi.nlm.nih.gov/pubmed/26925211
http://dx.doi.org/10.1039/c5sc03287c

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