Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

Tumour-initiating cells (TICs) are responsible for metastatic dissemination and clinical relapse in a variety of cancers(1,2). Analogies between TICs and normal tissue stem cells have led to the notion that activation of the normal stem-cell program within a tissue serves as the major mechanism for...

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Detalles Bibliográficos
Autores principales: Ye, Xin, Tam, Wai Leong, Shibue, Tsukasa, Kaygusuz, Yasemin, Reinhardt, Ferenc, Eaton, Elinor, Weinberg, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764075/
https://www.ncbi.nlm.nih.gov/pubmed/26331542
http://dx.doi.org/10.1038/nature14897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764075/
https://www.ncbi.nlm.nih.gov/pubmed/26331542
http://dx.doi.org/10.1038/nature14897

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