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Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
Tumour-initiating cells (TICs) are responsible for metastatic dissemination and clinical relapse in a variety of cancers(1,2). Analogies between TICs and normal tissue stem cells have led to the notion that activation of the normal stem-cell program within a tissue serves as the major mechanism for...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764075/ https://www.ncbi.nlm.nih.gov/pubmed/26331542 http://dx.doi.org/10.1038/nature14897 |